CSCs are a subpopulation of cancer cells known to be resistant to therapy and cause metastasis. The cancer stem cell theory posits that tumors are driven by specialized cancer cells called cancer stem cells (CSCs). Drug resistance culminating in relapse continues to be associated with fatal disease. ![]() ![]() Despite great strides being achieved in improving cancer patients’ outcomes through better therapies and combinatorial treatment, several hurdles still remain due to therapy resistance, cancer recurrence and metastasis.
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